A biocompatible betaine-functionalized polycation for coacervation
نویسندگان
چکیده
منابع مشابه
A Biocompatible, Heparin-binding Polycation for the Controlled Delivery of Growth Factors
Cationic peptides participate in many critical events in the body. Their importance in gene regulation, host defense, and many other processes has made them ideal targets to synthetically mimic. Over the years, a multitude of polycations have been synthesized, but a synthetic polycation that is biocompatible has yet to be realized. We created a synthesis platform that has resulted in a syntheti...
متن کاملCompact biocompatible quantum dots functionalized for cellular imaging.
We present a family of water-soluble quantum dots (QDs) that exhibit low nonspecific binding to cells, small hydrodynamic diameter, tunable surface charge, high quantum yield, and good solution stability across a wide pH range. These QDs are amenable to covalent modification via simple carbodiimide coupling chemistry, which is achieved by functionalizing the surface of QDs with a new class of h...
متن کاملGlucose-functionalized amino-OPEs as biocompatible photosensitizers in PDT.
Photodynamic therapy (PDT) is a minimally invasive procedure that can provide a selective eradication of neoplastic diseases by the combined effect of a photosensitizer, light and oxygen. New amino oligo(phenylene-ethynylene)s (OPEs), bearing hydrophilic glucoside terminations, have been prepared, characterized and tested as photosensitizers in PDT. The effectiveness of these compounds in combi...
متن کاملFunctionalized, biocompatible coating for superparamagnetic nanoparticles by controlled polymerization of a thioglycosidic monomer.
It is demonstrated that water-soluble, glucosylated poly(pentafluorostyrene) derivatives revealed favorable coating material properties for magnetic iron oxide nanoparticles. To prepare the coating material in high reproducibility and purity as well as in sufficient amounts, a new route of synthesis is established. The preparation and characterization of the glucosylated, tetrafluorostyryl mono...
متن کاملBiocompatible, surface functionalized mesoporous titania nanoparticles for intracellular imaging and anticancer drug delivery.
Mesoporous titania nanoparticles (MTNs) with excellent biocompatibility (LC(50)≈ 400 μg mL(-1)) and a large surface area (ca. 237.3 m(2) g(-1)) were synthesized and further functionalized with a phosphate-containing fluorescent molecule (i.e. flavin mononucleotide; FMN) and loaded with an anticancer drug (i.e. Doxorubicin) for successful intracellular bioimaging and drug delivery, respectively,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Soft Matter
سال: 2018
ISSN: 1744-683X,1744-6848
DOI: 10.1039/c7sm01763d